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Additionally, HIF-1 activates increased EPO expression, to induce expression of brain-derived neurotrophic factor (BDNF) and promote hippocampal neurogenesis ( Shh signaling pathway The sonic hedgehog (Shh) signaling pathway plays an important role in endogenous neurogenesis (38) and can play a neuroprotective role in ischemia-exposed brain injury through the activation of pathway proteins (39)

PMID: 37206992, PMCID: PMC10195105, DOI: 10.1007/s11884-022-00655-6

If you follow a vegetarian or vegan diet, you may not be getting adequate amounts of this nutrient from the food you eat, which may put you at risk of a deficiency

Archived from the original on April 16, 2023

Available from: Specific concomitant medical conditions may raise risk The injections are typically not given when certain complicating medical conditions are present, such as infections, tumors, or bleeding disorders