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RHONDA PATRICK: There are a lot of pathways

It does not cause hand tremors, heart palpitations, or sleep problems, so it can be used at any time of the day

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41-44 For this reason, Life Extension suggests most individuals strive to keep homocysteine levels below 12 mol/L, with less than 8 mol/L being considered ideal (although the latter may be difficult for some people to attain)

[36] [37] [38] A long-term study where vitamin B 12 was supplemented across a period of 10 years, led to lower levels of weight gain in overweight or obese individuals (p 20% of elderly individuals showed evidence of marginal vitamin B 12 depletion (serum vitamin B 12 : 148221 pmol/L)