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[DOI] [PubMed] [Google Scholar] 79.Wu Z., Heng J., Tian M., et al

Products in this category are commonly used as part of structured nutrition plans where supplements are taken consistently rather than only around workouts

COA / Lab results Evidence: Preclinical Pros Synthetic cyclic -MSH analogue activating MC1R/MC3R/MC4R/MC5R Stimulates melanogenesis without UV exposure Synthetic cyclic -MSH analogue activating MC1R/MC3R/MC4R/MC5R Stimulates melanogenesis without UV exposure Cons Not approved for human use by any major regulator Reported effects include nausea, blood-pressure changes and darkening/proliferation of moles Not approved for human use by any major regulator Reported effects include nausea, blood-pressure changes and darkening/proliferation of moles Pros and cons summarise available published data from peer-reviewed studies

(2018) 38:e198201

It could even contain contaminants as an unwelcome bonus