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The most noticeable effect observed after chronic THC exposure is the significant but reversible reduction in CB 1 Rs, with cortical regions showing more extensive decreases in expression (Hirvonen et al., 2012

Nanomedicine 13, 58875907

Anthocyanins and their metabolites as therapeutic agents for neurodegenerative disease

Among the seven conserved functional areas referred to as the Nrf2-ECH homology (Neh) domains of Nrf2, Neh1 primarily dimerises and attaches to small Maf (sMAF) proteins before going on to bind to DNA [13, 14]

Front Pharmacol 13:910292
