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Caffeine increases the circulation of these hormones and can eventually lead to high stress, depression, imbalanced hormones (adrenal and sex hormones), or low energy in the afternoon

B.Ru YuanX

PMID: 324 El-TananiYEl-TananiMRabbaniSABabikerRSatyamSM

[DOI] [PubMed] [Google Scholar] 138

This includes people with: Pernicious anaemia (autoimmune destruction of intrinsic factor-producing cells), typically requiring lifelong IM injections Crohn's disease or surgical resection affecting the terminal ileum Coeliac disease causing malabsorption (may improve with gluten-free diet) Chronic pancreatitis reducing enzyme availability needed for B12 release Vegans and strict vegetarians need reliable B12 sources through fortified foods or supplements, as plant-based diets contain negligible amounts of active B12