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Because cobalamin in normally absorbed from food through the gastrointestinal tract, chronic diseases that adversely affect the ability of the intestines to absorb nutrients (inflammatory bowel disease is an excellent example) can lead to cobalamin deficiency

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Vitamin B12 deficiency in over 16s: diagnosis and management (NG239) Rationale and impact

Often the output will be in a graph format, as we are showing what the body is doing to a drug over time
