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We identified distinct lipid distribution patterns across diverse brain regions that varied according to fatty acid chain length and degree of unsaturation

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PGI 2 , one of the prostanoids of arachidonic acid metabolism, is a potent vasodilator that inhibits platelet aggregation, leukocyte adhesion, and VSMC cell proliferation [87]

To date, with advancements in data types and modeling techniques, researchers have compiled a comprehensive understanding of various biomarkers of cellular and organ senescence, such as cell cycle arrest, altered cellular morphology, telomere attrition, and the SASP [26]