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After its conversion to acetyl-CoA , for example, pyruvate may serve as a precursor for fatty acid biosynthesis or for the synthesis of the amino acid alanine

[DOI] [PMC free article] [PubMed] [Google Scholar] 1095.Ruiz H.H., Nguyen A., Wang C., He L., Li H., Hallowell P., McNamara C., Schmidt A.M
Puerarin attenuates LPS-induced inflammatory injury in gastric epithelial cells by repressing NLRP3 inflammasome-mediated apoptosis
found that circ_0001273, as a cancer-promoting factor that upregulates SLC1A5 expression by binding to miR-622, which increases Gln uptake by tumor cells, consequently enhancing tumor growth and inhibiting cell apoptosis (57)

Concurrently, ROS can activate key inflammatory signaling pathways such as NF-B [477]
