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Integrating omics technologiessuch as metabolomics, transcriptomics, and pharmacogenomicsinto trial designs will enhance mechanistic understanding and treatment customization [301]

[DOI] [PubMed] [Google Scholar] 150.Safarpour S., Pirzadeh M., Ebrahimpour A., Shirafkan F., Madani F., Hosseini M., Moghadamnia A.A., Kazemi S

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These micelles, upon visible light activation, formed cross-linked cores that exhibited enhanced in vivo stability and prolonged blood circulation, ultimately leading to greater tumor accumulation

Additionally, SCFAs mediate bone mineralization and bone formation through the runt-related transcription factor (RUNX) signaling pathway, a key factor regulating the differentiation of osteoblast marker genes, which induces the directional differentiation of bone marrow stromal cells to bone and cartilage precursor cells (56)