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Targeting glutathione metabolism: partner in crime in anticancer therapy

Exogenous IGF-1 appears to activate them before they would naturally be activated

10.1242/jcs.173351 40 ColemanR.BrownJ.RathboneE.FlanaganL.ReidA.KendallJ.et al (2020)

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Targeted disruption of the mouse 3-phosphoglycerate dehydrogenase gene causes severe neurodevelopmental defects and results in embryonic lethality
