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The transition from the lipid environment of the BBB endothelial cell membrane to the aqueous interstitial fluid of the brains extracellular space necessitates further consideration of a drug and its delivery vehicles physicochemical properties, including size, surface charge, shape, and molecular weight (Sykova and Nicholson, 2008
doi: 10.3389/fped.2018.00373 194 Nagy-SzakalDWilliamsBLMishraNCheXLeeBBatemanLet al
GHK-Cu (50mg): A copper-binding tripeptide used in laboratory research involving peptidemetal interactions and copper-associated signalling pathways
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