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3 In a study using the rd1 mouse RP model, a mixture of antioxidants including alpha-tocopherol, ascorbic acid, Mn(III)tetrakis(4-benzoic acid)porphyrin and alpha-lipoic acid improved biomarkers of oxidative stress (protein carbonyl adducts and acrolein staining) and partially preserved cone function

It is developed in partnership with Rigi Care, Switzerland, and distributed by Azela Trading (Pty) Ltd, Cape Town

Additionally, the body weight of each mouse was measured four times per week to monitor potential treatment-related toxicity

2023 Jun 19

Physiological redox signaling operates within defined spatial and temporal limits, whereas sustained ROS overproduction overwhelms antioxidant buffering systems and causes lipid peroxidation, protein carbonylation, DNA damage, and neuronal dysfunction
