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TDP-43 is usually found in the nucleus, but in many cases of ALS it accumulates in the cytoplasm (TDP-43 proteopathy) (Thakur et al

10.1007/s10725-016-0235-2 Plant Growth Regul

High salt diet stimulates gut Th17 response and exacerbates TNBS-induced colitis in mice

As an example, GSTs protect cellular DNA against oxidative damage that can lead to an increase of DNA mutations or induce DNA damage promoting carcinogenesis 9
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