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Reactive oxygen species (ROS) include superoxide hydrogen peroxide (H 2 O 2 ), hydroxyl radical (OH ), hydroxyl ion (OH ), and hypochlorite ion (OCl )
Both of these heavy metalbased agents are extensively documented to induce severe oxidative stress and disrupt cellular glutathione levels [72, 73]
Arch Toxicol 58:225228
Front Cell Neurosci 12:256
