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PFAS catalyzes the glutamine-dependent amination of phosphoformylglycinamide ribonucleotide (FGAR) to FGAM through activation of the amide oxygen of FGAR by the -phosphate of ATP, leading to the formation of a monophosphate intermediate, followed by nucleophilic attack of ammonia generated from glutamine (Zhao et al., 2013)

A highly sensitive long-wavelength fluorescence probe for nitroreductase and hypoxia: selective detection and quantification

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196 During adipogenesis, C/EBP binds the Atg4b promoter, increasing Atg4b expression, enhancing LC3 processing, and facilitating the degradation of KLF2/3 through p62-mediated autophagy to promote adipocyte differentiation