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Let's start with understanding how peptides actually relieve pain

Nature 2009;460, 392-395, doi:10.1038/nature08221

There is increasing interest in developing tripeptides with targeted therapeutic functions, particularly for applications in wound healing [36, 75, 92], as well as in cancer [60, 170], neurodegenerative [24, 173], and cardiovascular diseases [177, 178], and in the design of functional foods [179, 182, 188]
doi: 10.1038/s41557-020-0465-9 232 ReddyK.ZamiriB.StanleyS

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