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Muscarinic receptor signaling and colon cancer progression

Neuronal NOS, nNOS Neuronal NOS (nNOS) is constitutively expressed in specific neurons within the brain and spinal cord

The application of L-NAME caused PHS in the treated chicks

Moving forward, aiming to better exploit the understanding of this fundamental pathway, we also outline the development of nanoparticle systems that show improvement in delivering approved drugs to the brain and how engineered nanoparticle formulations could aid in breakthroughs in terms of delivering emerging drugs and therapeutics while avoiding systemic adverse effects

Nature 416 , 291297 (2002)