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Subsequently, the reaction system was diluted with ethyl acetate (200 mL 3), followed by washing with water (100 mL 3) and saturated sodium chloride solution (100 mL 3)

doi: 10.1016/j.pharmthera.2020.107493 7 MensahGACroftJBGilesWH

Triggering vitamin toxicity is very rare, but it is possible

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Whitney K, Nikulina E, Rahman SN, Alexis A, Bergold PJ
