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Description
For example, mutations that hide the degron in oncoproteins result in a buildup of these proteins, which help them drive cancer formation and progression (Micel et al, 2013
Briefly, HEK293T packaging cells were transfected with control (firefly luciferase, GFP or shGFP) or target gene-expressing pLEX and pLenti constructs or pLKO shRNA constructs, together with pCMV-VSVG and pCMV-8.2 lentiviral packaging plasmids
PMID: 34281987 5-Hydroxytryptophan purchased from MedChemExpress
doi: 10.1182/blood-2016-10-569186
