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After antigen presentation, CD8+ T cells exert cytotoxic effects on pathogens by introducing a large payload of molecules such as granzymes and perforin, both of which induce apoptosis via cell membrane lysis

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McGregor et al

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Cell 170(6):1079-1095.e20

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Thus, high levels of FSP1 inhibit sorafenib-induced ferroptosis in HCC cells (95)

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