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Collectively, these findings suggest that coagulation factors, specifically ADAMTS13 and vWF, represent promising non-invasive biomarkers and potential therapeutic targets in the diagnosis and management of endometriosis, highlighting their role in hypercoagulability and chronic inflammation observed in the disease ( While a wide range of potential biomarkersincluding CA-125, various microRNAs, and immune-related moleculeshave been identified for the diagnosis and monitoring of endometriosis, their clinical utility remains limited ( Emerging approaches involving biomarker panels and multi-omics technologies (such as proteomics and miRNA expression profiling) offer promising avenues for improving diagnostic accuracy