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The genetic spectrum of a cohort of patients clinically diagnosed as Parkinsons disease in mainland China

154 The relatively low mechanical stress (about 45 Pa) derived by the ECM can stimulate the stem cell signaling pathway via the cytoskeleton/AIRE axis by activating the integrin beta 1/3 receptor, while excessive mechanical stress (~450 Pa) induces quiescence in BCSCs dependent on DDR2/STAT1/P27 signaling, which may explain conflicting results observed in previous individual studies

Recommendation: Intramuscular injection with dosage determined during consultation

doi: 10.1038/nrgastro.2015.47

Please credit the National Center for Complementary and Integrative Health as the source