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Ideally, islet-cell autoantibodies screening should be performed in subjects with newly diagnosed T2DM, ensuring a closer monitoring of those resulted positive and avoiding treatment of hyperglycaemia which might increase the rate of -cells loss

Baicalein Protects Human Melanocytes from H2O2-Induced Apoptosis via Inhibiting Mitochondria-dependent Caspase Activation and the P38 MAPK Pathway
A study comparing five methods for the determination of 2,3-DPG in blood, which included a colorimetric method, two enzymatic endpoint methods and two enzymatic rate-dependent methods, concluded that there were no statistically significant differences between them (Reference Teunissen, De Leeuw and Boink81)

27 Our study revealed that some mild adverse events occurred in the first four weeks, although this occurrence was not statistically significant
doi: 10.1136/pgmj.74.877.702
