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However, immunoassays for measurement of 8-OHdG and F2-isoP have been criticized, although results employing this technology being widely published

Provider monitoring and dose adjustment are mandatory in hepatic or renal compromise

doi: 10.1007/s10753-021-01562-4

High-abundance polypeptides of the human plasma proteome comprising the top 4 logs of polypeptide abundance
This means you need concentrations that support single-draw dosing at these levels