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[45] on peripheral blood mononuclear cells (PBMCs) isolated from MS patients showed that luteolin dose-dependently reduced PBMCs proliferation as well as production of IL-1, TNF-, and matrix metalloproteinase-9 (MMP-9), the inflammatory factors that are crucial in MS

Once internalized, zinc can bind to intracellular proteins, be transiently stored or be released into circulation
