modifications to thiol on glutathione Thiol−Disulfide Exchange between Glutaredoxin and Low-molecular-weight thiol transferases in redox
Description
If you read the literature, so many conditions are associated with low glutathione

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It contributes to the induction of ER stress

W., Kim, M.-S., Cho, L

Effect of riboflavin deficiency on development of the cerebral cortex in Slc52a3 knockout mice
