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V., Calcia, M

doi: 10.3389/fmed.2018.00316

The entire cage of mice was not used for the project if any mice in the cage showed signs of stress, such as over-grooming or fighting during the adaptation period, in order to maintain consistency across all treatment and control groups

In addition, de novo sphingolipid biosynthesis is essential for autophagy induction in macrophages, which plays a protective role by clearing excess lipids from LDs through the turnover of ORMDL sphingolipid biosynthesis regulator 1 (ORMDL1) protein, a negative regulator of serine palmitoyl-CoA transferase activity (Wang et al., 2015b)

By donating an electron to unstable molecules, it helps maintain the delicate balance of oxidation and reduction within cells, a process crucial for proper cellular function