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Global Prevalence 6-12% of adults under 60 suffer from Vitamin B12 deficiency

In esophageal cancer, CD38 expression on myeloid-derived suppressor cells (MDSC) discriminates between MDSC with high and low immunosuppressive function on T cells [53]

Effectiveness: Vitamin B12 Injection is an effective medication for treating vitamin B12 deficiency when used appropriately under the guidance of a healthcare provider

NAD+ supports neuroprotection by repairing DNA damage, reducing oxidative stress, and promoting the function of brain cells

3.4 Changes in serum homocysteine by supplementation route and dosage Analysis of 10 comparisons showed that vitamin B12 supplementation was associated with a mean reduction of 35.8% in serum homocysteine concentrations (Supplementary Table S5)