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After administration, 6-OHDA is absorbed into neurons by dopaminergic and noradrenergic transporters due to its structural similarities to dopamine and noradrenaline (Luthman et al., 1989)
In inflammatory reactive astrocytes co-cultured with brain endothelial cells nicotine-evoked Ca(2+) transients are attenuated due to interleukin-1beta release and rearrangement of actin filaments
