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Administration Of Dose The dose & duration of treatment depends on the medical condition

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Possible etiological factors include increased interleukin production stimulated by toxic uremic milieu, oxidative stress, acidosis, and decreased clearance of inflammatory cytokines by the kidneys [28,29,30]

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The H-bond network is only observed for OCTN2 in the occluded conformation and is absent in the inward-facing conformation, supporting that the network helps to stabilise a kinked conformation of TM11 that packs against TM2