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Liu et al., 2021) (202, 204)
We speculate that the absence of hormetic triggers in modern life will decrease the transcription of NRF1 and NRF2, subsequently TFAM and mitochondrial transcription factor B2 (TFB2M), and ultimately leading to a decrease in mitochondrial mass (Kokura et al., 2007
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Science 349 , 195198 (2015)
