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Those intermediates include malate, citrate, -ketoglutarate and succinate [40, 41]

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While 52% of these 26 patients (22% of the total) presented with mucosal changes, glossitis was specifically seen in 31% (19 out of 63), hyperpigmentation of the skin in 19% (12 out of 63), hair changes in 9% (6 out of 63), angular stomatitis in 8% (5 out of 63), and lastly, vitiligo was seen in only 3% (2 out of 63) [10]

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It creates the active form of folate and helps balance neurotransmitters, hormones, and antioxidants A SNP refers to a single nucleotide variant at a location in the human genome

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