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An increased Firmicutes/Bacteroidetes ratio might be involved in inducing inflammation, as this is observed in several inflammatory conditions and as this ratio is shown to be positively associated with dysregulated humoral and cellular immunity (188, 189)

The phenolic-rich extracts obtained through this method hold potential for use in functional beverages and as natural preservative additives (154)

Additionally, estrogen-stimulated cyclooxygenase-2 (COX-2) activity drives prostaglandin E2 (PGE2) synthesis, creating a positive feedback loop that enhances local estrogen production and inflammation, further facilitating ectopic implantation ( 2.2 Immune system dysfunction and chronic inflammation Immune system dysfunction and chronic inflammation are central pathological features underlying endometriosis-associated infertility, characterized by aberrant immune cell activation, cytokine dysregulation, and impaired immune surveillance

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So when GGT is elevated, it often indicates that your liver's antioxidant defense system is under strain