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In the absence of marked cardiovascular, liver, and renal impairment on ICU admission, we considered that the time-course of blood lactate concentrations could be related almost exclusively to the time-course of VPA concentrations

Reaction of carnosine with aged proteins: another protective process

In principle, L-carnitine can also fulfill other functions which are generally attributed to it, in addition to its ability to cross the blood-brain barrier

We found a significant decline in mRNA expression of PGC-1, ERR and Tfam at times when left ventricular ejection fraction was still preserved (unpublished observations), suggesting repressed mitochondrial biogenesis pathways in compensated hypertrophy

L-carnitine can be accumulated by liquid deep culture or solid fermentation of microorganisms such as yeast, Aspergillus, Penicillium, and Rhizopus