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The enrichment network diagram showed that the upregulated genes ultimately pointed to physiological activities, including defence response to the viruses, defence response to symbiont innate immune response, and regulation of defence response [Fig
A previous estimate [42] suggested that oxidative stress plays a role in the pathophysiology of over 200 clinical conditions
[DOI] [PMC free article] [PubMed] [Google Scholar] Martin M.N., Tarczynski M.C., Shen B., Leustek T
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The citric acid cycle appears vulnerable to increases in the NADH/NAD+ ratio, as three NADH sensitive enzymes (-ketoglutarate dehydrogenase, isocitrate dehydrogenase, and citrate synthase) are prone to inhibition by elevations in the NADH/NAD+ ratio (45)
