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153 In a collagen-induced arthritis (CIA) model, histopathological analysis revealed no significant degeneration of chondrocytes in the cartilage in the neutrophil membrane nanoparticle-treated group, The number of fibroblast-like synoviocytes (FLS) positive for staining was significantly reduced

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(103) showed that roxadustat (HIF prolyl hydroxylase inhibitor) stabilizes HIF-1/Nrf2, reducing ferroptosis, inflammation, and fibrosis in folic acid-induced renal injury

The asymmetrical synergistic interaction of chronic stress and TBI has been utilized to create models of repetitive mild TBI and chronic stress to simulate neurodegenerative tauopathy like CTE, and examine potential disease modifying therapeutic using Fyn kinase inhibition via modulation of tau phosphorylation (Tang et al., 2020