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Hypomagnesemia induced by several proton-pump inhibitors

It has antioxidant effects, is a co-factor in mitochondrial energy metabolism, and contributes to DNA synthesis, the methylation cycle, and epigenetic regulation.12 B 12 is present in foods of animal origin, such as meat, eggs, and milk, or via food fortification

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Initiate supplementation with oral folic acid and intramuscular vitamin B12 to reduce the severity of hematologic and gastrointestinal toxicity of Pemetrexed Injection