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The low-irritant formulation means it suits a range of skin types, though as with any new product, patch-test first if you have very reactive skin

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Since then, it has become clear that baseline impedance, measured by multichannel intraluminal impedance (MII) testing is lower in GERD patients compared to healthy volunteers and improves with medical and surgical therapy (53, 54)

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Nonimmunized mice received similar injections but without the antigen CII