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Despite curcumin has medicinal potential, resolving a few issues is necessary to effectively utilize its neuroprotective advantages

For decades, tetrabenazine and reserpine were the only drugs available in that class, with preference to the former because of its selectivity for VMAT2 over VMAT1 binding, reversibility, and shorter duration of response, decreasing adverse effects

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Figure 2 Figure 3 Figure 4 Figure 5 Figure 6 Figure 7 Figure 8 Figure 9 4 Conclusions and perspective Inadvertently, the field of research is gradually focusing on smaller organisms, microbiomes are making their way onto the research scene, and the intestinal microbiota, mainly nonculturable bacteria, play a role in improving a healthier intestinal ecology by exerting their innate local and adaptive immune superiority

Jun 26 2024;385:e079061
