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While the percentage of the total cell GSH content found in mitochondria is minor (1015%), the mitochondrial glutathione (mGSH) concentration is similar to that found in the cytosol

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Chalmers JD, Smith MP, McHugh BJ, Doherty C, Govan JR, Hill AT

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Thus, future research should consider the impact of interacting intrinsic genetic as well as extrinsic dietary factors involved in the regulation of IIS

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Histone lactylation: from tumor lactate metabolism to epigenetic regulation

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