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Several studies of HCC cells have shown that inhibition of NFE2L2 expression can increase the anticancer activity of the chemicals erastin and sorafenib, with inhibition of NFE2L2 inducing ferroptosis and killing HCC cells (64)

doi: 10.1016/j.taap.2025.117266 118 WeidleUHBirzeleFKrgerA

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Gilbert (eds)

Therapeutic strategies to address neuronal nitric oxide synthase deficiency and the loss of nitric oxide bioavailability in Duchenne Muscular Dystrophy
