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This upregulation results in a substantial accumulation of intracellular Fe2+, causing tissue damage (127)

doi: 10.1155/2021/6631805

This finding is supported by evidence obtained from clinical and animal studies suggested an association between oxidative stress and development of diabetic cataract [59,60]

Numerous studies have proved that carotenoid biosynthesis is regulated by a variety of transcription factor families, including the R2R3-MYB, MADS-box, NAC, bHLH, SBP-box, AP2/ERF, HD-ZIP, NF-Y, and WRKY ( (Rin) , non-ripening ( Nor ), and colorless non-ripening (Cnr) promote our current understandings of the mechanisms underlying fruit ripening ( SlSGR1 and SlGgpps2 genes and activating their expression ( SlAPRR2 and SlGLK1 genes in tomato increased the number of plastids in fruit and carotenoid accumulation in fruit at ripening stage was higher than that of wild type ( SlNAC1 in tomato resulted in up-regulation of the expression of SIPSY1 and accumulation of total carotenoids

The TFAP2A-S100A2 axis has been demonstrated to promote LUAD metastasis by regulating glutamine metabolism