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17 Mechanistically, competition strategies among bacteria that produce antibiotics and small metabolites like phenazines that limit the growth of other bacterial species may have off-target effects on mitochondrial homeostasis, leading to ROS, protein damage, and neurodegeneration

The other drawback is that some people who are sensitive to higher histamine levels or who have mast cell activation syndrome report that NAC gives them a histamine reaction

Dosage ranges from 0.5 mg per day for general wellness up to 2 to 3 mg per day for wound healing

S., Schell, T

This effect is enhanced when combined with Vitamin C, which boosts glutathione absorption