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Either the GHK-CU isn't suitable for your biochemistry, your protocol needs adjustment, or an external factor is interfering

The review of versatile application of collagen

Fatty Acids 2008, 79 (6), 215222

carried out a study in a sheep model, in which restricted dietary methyl donor (i.e., methionine and vitamin B12) provision up to day 6 following insemination in sheep altered DNA methylation and led to hypertensive and insulin-resistant offspring (39)

Otherwise, a copper dyshomeostasis may contribute to a plethora of pathological conditions
