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Furthermore, GHD may occur as isolated GHD or with multiple pituitary hormone deficiencies

Studies have shown that ferroptosis is linked to elevated prostaglandin-endoperoxide synthase 2 (PTGS2) expression and prostaglandin E2 (PGE2) secretion, which accelerates arachidonic acid metabolism, releasing inflammatory mediators and activating the inflammatory response [11]

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Some models also report improved total antioxidant capacity (TAC) and normalization of inflammatory cytokine levels

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