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They further interfered with LAMP-2A and found that the up-regulation of Nrf2 in knockout SNX10 mice depends on CMA activation, thereby reducing alcohol-induced liver damage and steatosis (You et al., 2018)
The mechanistic rationale is dual-receptor stimulation: GHRH receptor activation by the GHRH analogue plus ghrelin-receptor activation by the GHRP
10.1016/j.cmet.2017.07.001 304 WooC
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The GLP-1 receptor antagonist Ex9 acutely reduced somatostatin secretion with 50% in wild-type mice (Fig
