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doi: 10.2337/diabetes.47.10.1555

PTP1B is a negative regulator of the leptin and insulin signaling pathways, so it has emerged as an attractive novel target for the treatment of both type 2 diabetes and obesity [51]

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Matrix biology and tissue regeneration , especially where proteoglycan, collagen, and extracellular matrix synthesis are endpoints of interest, such as in cartilage or bone models
