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Urinary biomarkers offer a promising avenue in this context, providing deeper insight into the complex and multifactorial pathophysiology of DKD

Trials with high or unclear risk of bias in the first three criteria were deemed high risk

doi:10.1161/01.ATV.0000146266.65820.a1 182

The brains phosphatidylserine content appears to diminish with aging, 179 and several clinical trials in older adults with self-reported memory concerns have found phosphatidylserine supplementation, at 300 mg per day, can improve memory and other aspects of cognitive function

Studies increasingly point to creatine playing a broader role in supporting muscle performance, cellular energy, and brain health related to mental alertness, attention, and mood