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High-dose monotherapy or combinations are used for insufficient pain relief, but tolerability issues limit the benefits, leading to high discontinuation rates [166,180,181,182]
Assessment of neurodegeneration and neuronal loss in aged 5XFAD mice. STAR protocols vol
Kim TW, Lim BV, Baek D, Ryu DS, Seo JH
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10.1038/s41419-021-04227-0 24 KuboH.AsaiK.KojimaK.SugitaniA.KyomotoY.OkamotoA.et al (2019)
