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doi:10.1016/j.pain.2013.11.013 9

Regarding blood pressure, isoprenaline control rats exhibited intracranial (superior sagittal sinus) hypertension, portal and caval hypertension, and aortal hypotension
The researchers report this is not due to an increase in T levelsin fact, T levels dipped over this period of time in much of the evidence they reviewed

Neither form should be used casually

When the immune system is already dysregulated, introducing compounds that modulate immune function carries inherent risks